KEGG: Kyoto Encyclopedia of Genes and Genomes
http://www.genome.ad.jp/kegg/

A grand challenge in the post-genomic era is a complete computer representation of the cell, the organism, and the biosphere, which will enable computational prediction of higher-level complexity of cellular processes and organism behaviors from genomic and molecular information. Towards this end we have been developing a bioinformatics resource named KEGG as part of the research projects of the Kanehisa Laboratories in the Bioinformatics Center of Kyoto University and the Human Genome Center of the University of Tokyo. This has been added to Biological Informatics Subject Tracer™ Information Blog.